I recently purchased a 7 port Ankar powered USB Hub. All was fine with my original layout, but yesterday, I decide to layout my devices to reduce clutter. Just after completing the rearrangement of devices on my desktop, I started having trouble with my WiFi dropping and then not being able to reconnect. Shortly thereafter, my Apple Magic Mouse began disconnecting.
I dutifully shutdown my Mini, disconnected all the devices, ran hardware diagnostics, booted in single user mode, cleared the SMC, etc. Could not find any problems. Mac booted properly, mouse worked properly, WiFi connected. What the heck was going on? I changed out my Crucial memory with the original Apple memory. The Mac with no devices was working properly.
I started reattaching devices, first connecting the Ankar hub, then external drives, Apple Superdrive, etc. Boom! WiFi went flakey. While turning off the WiFi, my Magic Mouse disconnected. Rebooting gave me a completely blank screen with only a mouse cursor. Things appeared to be going down hill quickly and I was not happy, because I had planned to put 20 or 30 miles on my bike in the sunshine.
So I stripped down the Mini again. Turned off the magic mouse. Plugged in a USB mouse. Plugged in a wired network cable. Booted. Managed to log in. Turned off WiFi on the Mini. Turned on the Magic Mouse. It connected properly. Unplugged the USB Mouse. Started plugging in devices. Everything continued to work. Left the WiFi off. Rebooted. The Mini came up and I could log on just fine with the wired network cable. Decided not to tempt fate and left the WiFi turned off.
My (incomplete and unsubstantiated) conclusion was that rearranging the Mini, with all the USB devices sitting close by on the Ankar hub was causing interference with all of the wireless devices I was using. Since the Mini is not really portable, I decided to leave the network cable plugged in and turn off the WiFi. However, I'm not super happy about this, because the Mac no longer syncs with my iPhone over WiFi.
I'll settle in with this setup for a while, until I can figure out what to do with all of my USB devices.